Vaccination with recombinant oncosphere antigens reduces the susceptibility of sheep to infection with Taenia multiceps
نویسندگان
چکیده
منابع مشابه
Immunization of sheep against the larval stage of Taenia multiceps.
A trial with 200 ewes and 127 lambs showed that vaccination of lambs with 2 doses of Oncosphere Secretory Antigen (OSA) 4 weeks apart, at either 4-8 and 8-12 weeks or at 12-16 and 16-20 weeks of age, was equally effective in protecting them against infestation with the larval stage of Taenia multiceps. In this trial, the lambs of ewes, vaccinated with OSA when they were 90 and again 120 days pr...
متن کاملInduction of protection against porcine cysticercosis by vaccination with recombinant oncosphere antigens.
Two recombinant Taenia solium oncosphere antigens, designated TSOL18 and TSOL45-1A, were investigated as vaccines to prevent transmission of the zoonotic disease cysticercosis through pigs. Both antigens were effective in inducing very high levels of protection (up to 100%) in three independent vaccine trials in pigs against experimental challenge infection with T. solium eggs, which were under...
متن کاملProtection against Taenia pisiformis larval infection induced by a recombinant oncosphere antigen vaccine.
Taenia pisiformis larvae cause significant health problems to rabbits. At present, it is not known whether the recombinant antigen from the T. pisiformis oncosphere is able to confer protective immunity against T. pisiformis larval infection. The full-length cDNA was cloned into a pET32a (+) vector, and the recombinant protein was then expressed in BL21 (DE3) cells. Vaccination with the purifie...
متن کاملPrevalence of antibodies to unique Taenia solium oncosphere antigens in taeniasis and human and porcine cysticercosis.
The presence of two oncosphere antigens (OAs) of 22.5 and 31.3 kD in whole and excretory/secretory (ES) OA preparations of both Taenia solium and T. saginata or in antigen preparations from T. solium metacestodes or immature tapeworms was assessed. This included an evaluation of whether antibodies to other cestodes cross-reacted to these OAs. The OAs were present in whole oncosphere extract and...
متن کاملProtection of ewes against Teladorsagia circumcincta infection in the periparturient period by vaccination with recombinant antigens.
Teladorsagiosis is a major production-limiting disease in ruminants in temperate regions throughout the world and one of the key interventions in the management of the disease is the prevention of pasture contamination with Teladorsagia circumcincta eggs by ewes during the periparturient relaxation in immunity which occurs in the period around lambing. Here, we describe the immunisation of twin...
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ژورنال
عنوان ژورنال: International Journal for Parasitology
سال: 2008
ISSN: 0020-7519
DOI: 10.1016/j.ijpara.2007.11.006